An inhibitor of MMP-9; a derivative of tetracycline; inhibits MMP-9 activity in a dose-dependent manner in an assay for collagen degradation; completely inhibits neutrophil-derived MMP-9 degradation of denatured collagen at a concentration of 500 μg/ml; lacks antibiotic activity

4-Epianhydrochlortetracycline (hydrochloride) – 1 mg

Brand:
Cayman
CAS:
158018-53-2
Storage:
-20
UN-No:
Non-Hazardous - /

4-Epianhydrochlortetracycline is a derivative of tetracycline (Item No. 14328).{41116} It inhibits matrix metalloproteinase-9 (MMP-9) activity in a dose-dependent manner in an assay for collagen degradation. 4-Epianhydrochlortetracycline also completely inhibits neutrophil-derived MMP-9 degradation of denatured collagen at a concentration of 500 μg/ml. Unlike tetracycline, 4-epianhydrochlortetracycline lacks antibiotic activity.  

 

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SKU: 23146 - 1 mg Category:

Description

An inhibitor of MMP-9; a derivative of tetracycline; inhibits MMP-9 activity in a dose-dependent manner in an assay for collagen degradation; completely inhibits neutrophil-derived MMP-9 degradation of denatured collagen at a concentration of 500 μg/ml; lacks antibiotic activity

Formal name: (4R,4aS,12aS)- 7-chloro-4-(dimethylamino)-1,4,4a,5,12a,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide, monohydrochloride

Synonyms: 

Molecular weight: 497.3

CAS: 158018-53-2

Purity: >95%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Cell Biology|ECM & Adhesion Molecules||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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