A natural type B trichothecene produced by certain species of the fungus Fusarium; inhibits protein biosynthesis

4-deoxy Nivalenol – 1 mg

Brand:
Cayman
CAS:
51481-10-8
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

4-deoxy Nivalenol is a natural type B trichothecene produced by certain species of the fungus Fusarium, particularly those found on cereal crops, including wheat, barley, oats, maize, and rye.{24416,24414} This mycotoxin can induce vomiting, diarrhea, and weight loss as well as other physiological and toxicological effects.{24415} It inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity.{24417} It passes the blood-brain barrier at different rates in different animals and this may be related to anorexia.{24415}  

 

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SKU: 11428 - 1 mg Category:

Description

A natural type B trichothecene produced by certain species of the fungus Fusarium; inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA; passes the blood-brain barrier at different rates in different animals

Formal name: 12,13-epoxy-3α,7α,15-trihydroxy-trichothec-9-en-8-one

Synonyms:  DON|NSC 269144|Vomitoxin

Molecular weight: 296.3

CAS: 51481-10-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Toxins|Mycotoxins||Research Area|Toxicology|Cell Health & Viability||Research Area|Toxicology|Environmental|Agriculture

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