4-Aminohippuric acid is a substrate for various renal transporters that has been used in the study of anion uptake in the kidney. It is a substrate for organic anion transporter 1 (OAT1; Km = 14.3 µM in X. laevis oocytes), the human inorganic phosphate transporter (NPT1; Km = 2.66 mM in HEK293 cells), and apical multidrug resistance protein (MDR2; Km = 880 µM in HEK293 cells).{38433,38434,38432} 4-Aminohippuric acid is a glycine amide form of 4-aminobenzoic acid (Item No. 18659). Formulations containing 4-aminohippuric acid have been used as markers to determine renal plasma flow.
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A substrate for OAT1 (Km = 14.3 µM), NPT1 (Km = 2.66 mM), and MDR2 (Km = 880 µM); a glycine amide form of 4-aminobenzoic acid
Formal name: N-(4-aminobenzoyl)-glycine
Synonyms: p-Aminohippuric Acid|para-Aminohippuric Acid|NSC 13064|NSC 7550
Molecular weight: 194.2
CAS: 61-78-9
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Cardiovascular System|Kidney & Renal Disease
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