3-Thiopheneacrylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
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3-Thiopheneacrylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
Formal name: 3-(3-thienyl)-2-propenoic acid, methyl ester
Synonyms: 3-Thiophen-3-yl-Acrylic Acid methyl ester
Molecular weight: 168.2
CAS: 135835-43-7
Purity: >98%
Formulation: A crystalline solid
Product Type|Biochemicals|Synthetic Intermediates & Building Blocks
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The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression.{17508} Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to bind tetO and block transcription.{17509,17510} Anhydrotetracycline (hydrochloride) is a powerful effector in both the tetracycline repressor (TetR) and reverse TetR (revTetR) systems, binding the Tet repressor 35-fold more strongly than Tet.{17508,17511} Moreover, anhydrotetracycline poorly binds the 30S ribosomal subunit, compared to Tet,{17512} so it does not act as a general inhibitor of translation and is a poor antibiotic. Perhaps related to this, the concentration of anhydrotetracycline that inhibits eukaryotic cell growth is more than a 1,000-fold above the dose that alters transcription through TetR.{17508}
Available on backorder