3-thia TDA is an analog of the 14-carbon saturated fatty acid myristic acid

3-Thiatetradecanoic Acid – 5 mg

Brand:
Cayman
CAS:
116296-31-2
Storage:
-20
UN-No:
Non-Hazardous - /

3-Thiatetradecanoic acid (3-thia TDA) is an analog of the 14-carbon saturated fatty acid myristic acid, wherein the C-3 carbon has been replaced by sulfur in a thioether linkage. When chronically administered to rats, 3-thia TDA acts as a peroxisome inducer (PPAR ligand), increases fatty acid oxidation, and lowers plasma lipid levels.{3828} Incorporation of 3-thia TDA into dietary regimens at 150 and 300 mg/kg in rats induces the formation of oleic acid via Δ9-desaturase, and dose-dependently increases Δ9-desaturase mRNA levels.{4942}  

 

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Description

3-thia TDA is an analog of the 14-carbon saturated fatty acid myristic acid, wherein the C-3 carbon has been replaced by sulfur in a thioether linkage. When chronically administered to rats, 3-thia TDA acts as a peroxisome inducer (PPAR ligand), increases fatty acid oxidation, and lowers plasma lipid levels.{3828} Incorporation of 3-thia TDA into dietary regimens at 150 and 300 mg/kg in rats induces the formation of oleic acid via .DELTA.9-desaturase, and dose-dependently increases .DELTA.9-desaturase mRNA levels.{4942}

Formal name: (undecylthio)-acetic acid

Synonyms:  3-TDA

Molecular weight: 246.4

CAS: 116296-31-2

Purity: ≥98%

Formulation: A crystalline solid

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