Limaprost is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is an inhibitor of ADP and collagen-induced platelet aggregation and is 10-1

3-methoxy Limaprost – 10 mg

Brand:
Cayman
CAS:
1224443-96-2
Storage:
-20
UN-No:
Excepted Quantity - 1231 / 3

Limaprost is an analog of prostaglandin E1 (PGE1) with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is an inhibitor of ADP and collagen-induced platelet aggregation and is 10-1,000 times more potent than PGE1 as an inhibitor of platelet adhesiveness measured in vitro.{6808} 3-methoxy Limaprost results from the Michael addition of methanol to the limaprost 2,3 double bond. The resulting novel compound is likely to retain FP receptor agonist activity; however there are no published studies of the pharmacological properties of 3-methoxy limaprost.  

 

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SKU: 10008445 - 10 mg Category:

Description

Limaprost is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is an inhibitor of ADP and collagen-induced platelet aggregation and is 10-1,000 times more potent than PGE1 as an inhibitor of platelet adhesiveness measured in vitro.{6808} 3-methoxy Limaprost results from the Michael addition of methanol to the limaprost 2,3 double bond. The resulting novel compound is likely to retain FP receptor agonist activity; however there are no published studies of the pharmacological properties of 3-methoxy limaprost.

Formal name: 3-methoxy-11α,15S-dihydroxy-17S,20-dimethyl-9-oxo-prosta-13E-en-1-oic acid

Synonyms:  3-methoxy-17α,20-dimethyl-Δ2-Prostaglandin E1|3-methoxy-2,3-dihydro-Limaprost

Molecular weight: 412.6

CAS: 1224443-96-2

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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