A p-terphenyl fungal metabolite; has a 96% scavenging effect on DPPH radicals at 100 μg/ml; inhibits the growth of HeLa cervical

3-Hydroxyterphenyllin – 1 mg

Brand:
Cayman
CAS:
66163-76-6
Storage:
-20
UN-No:
Non-Hazardous - /

3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.{42907,42908,38480,37200} It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals (DPPH; Item No. 14805) when used at a concentration of 100 μg/ml.{42908} 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methicillin-resistant S. aureus (MRSA) and V. vulnificus bacteria (MIC = 31 μg/ml for both).{38480} It also inhibits HIV-1 integrase in both coupled and strand transfer assays (IC50s = 2.8 and 12.1 μM, respectively).{37200}  

 

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SKU: 28502 - 1 mg Category:

Description

A p-terphenyl fungal metabolite; has a 96% scavenging effect on DPPH radicals at 100 μg/ml; inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as MRSA and V. vulnificus bacteria (MIC = 31 μg/ml for both); inhibits HIV-1 integrase in both coupled and strand transfer assays (IC50s = 2.8 and 12.1 μM, respectively)

Formal name: 3′,6′-dimethoxy-[1,1′:4′,1”-terphenyl]-2′,3,4,4”-tetrol

Synonyms:  NSC 299113

Molecular weight: 354.4

CAS: 66163-76-6

Purity: ≥70%

Formulation: A solid

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