A precursor that is used in the synthesis of HMG-CoA; also used in the synthesis of 3-alkyl-3-hydroxyglutaric acids that act as inhibitors of HMG-CoA reductase

3-hydroxy-3-Methylglutaric anhydride – 100 mg

Brand:
Cayman
CAS:
34695-32-4
Storage:
-20
UN-No:
Non-Hazardous - /

The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase mediates the rate-limiting step in cholesterol synthesis, converting HMG-CoA to mevalonate.{30161} 3-hydroxy-3-Methylglutaric anhydride is a precursor that is used in the synthesis of HMG-CoA.{30160,30159} It has also been used in the synthesis of 3-alkyl-3-hydroxyglutaric acids that act as inhibitors of HMG-CoA reductase.{30158}  

 

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Description

A precursor that is used in the synthesis of HMG-CoA; also used in the synthesis of 3-alkyl-3-hydroxyglutaric acids that act as inhibitors of HMG-CoA reductase

Formal name: dihydro-4-hydroxy-4-methyl-2H-pyran-2,6(3H)-dione

Synonyms:  Dicrotalic anhydride|HMG anhydride

Molecular weight: 144.1

CAS: 34695-32-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Synthetic Intermediates & Building Blocks||Research Area|Cardiovascular System|Lipids & Lipoproteins|Cholesterol Metabolism

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