An acetaminophen-protein adduct; has been found in isolated human serum following therapeutic and supratherapeutic doses of acetaminophen and in the presence and absence of hepatotoxicity; decreases renal GSH levels

3-Cysteinylacetaminophen (trifluoroacetate salt) – 5 mg

Brand:
Cayman
CAS:
1331891-93-0
Storage:
-20
UN-No:
Non-Hazardous - /

3-Cysteinylacetaminophen is an acetaminophen-protein adduct formed during the metabolism of acetaminophen (Item No. 10024).{32385,47103} 3-Cysteinylacetaminophen has been found in isolated human serum following therapeutic and supratherapeutic doses of acetaminophen and in the presence and absence of hepatotoxicity.{47104,47105} In mice, 3-cysteinylacetaminophen decreases renal glutathione (GSH) levels, an effect that can be blocked by the γ-glutamyl inhibitor acivicin (Item No. 14003).  

 

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SKU: 26388 - 5 mg Category:

Description

An acetaminophen-protein adduct; has been found in isolated human serum following therapeutic and supratherapeutic doses of acetaminophen and in the presence and absence of hepatotoxicity; decreases renal GSH levels

Formal name: S-[5-(acetylamino)-2-hydroxyphenyl]-L-cysteine, trifluoroacetate salt

Synonyms:  3-(cysteine-S-yl)acetaminophen|APAP-Cys

Molecular weight: 384.3

CAS: 1331891-93-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Neuroscience|Pain Research||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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