A product of protein oxidation; a marker of eosinophil peroxidase-induced protein oxidation in vitro and in vivo

3-Bromotyrosine (trifluoroacetate salt) – 5 mg

Brand:
Cayman
CAS:
2320428-62-2
Storage:
-20
UN-No:
Non-Hazardous - /

3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response.{39006,39007,39009} It has been used as a marker of eosinophil peroxidase-induced protein oxidation in vitro and in vivo.{39007,39010} In addition to its production in eosinophils, 3-bromotyrosine is found at 5-fold higher levels in peritoneal exudate from mice infected with K. pneumoniae compared with uninfected animals, suggesting neutrophils release higher levels of oxidized products during inflammation.{39011} In a human study, 3-bromotyrosine was increased 10-fold in allergen-challenged lung samples from subjects with allergen-induced asthma.{39007}  

 

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Description

A product of protein oxidation; a marker of eosinophil peroxidase-induced protein oxidation in vitro and in vivo

Formal name: 3-bromo-L-tyrosine, monotrifluoroacetate salt

Synonyms:  3-bromo-Tyr

Molecular weight: 374.1

CAS: 2320428-62-2

Purity: ≥95%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia||Research Area|Oxidative Stress & Reactive Species|Protein Oxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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