A selective 5-LO inhibitor (IC50 = 1.5 µM) that demonstrates anti-inflammatory

3-acetyl-11-keto-β-Boswellic Acid – 5 mg

Brand:
Cayman
CAS:
67416-61-9
Storage:
-20
UN-No:
Non-Hazardous - /

3-acetyl-11-keto-β-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree B. serrata (frankincense).{30044} It selectively inhibits 5-lipoxygenase (IC50 = 1.5 µM) in an enzyme-directed, nonredox, and noncompetitive manner.{6066} 3-acetyl-11-keto-β-Boswellic acid and other members of the boswellic acid family have been studied for potential use in the control of inflammatory diseases, including arthritis and cancer.{30048,30047,30045,30046}  

 

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SKU: 11672 - 5 mg Category:

Description

A selective 5-LO inhibitor (IC50 = 1.5 µM) that demonstrates anti-inflammatory, anti-arthritic, and anti-cancer actions

Formal name: (3α,4β)-3-(acetyloxy)-11-oxo-urs-12-en-23-oic acid

Synonyms:  3-O-acetyl-11-keto-β-Boswellic acid|AKBA

Molecular weight: 512.7

CAS: 67416-61-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Prenol Lipids||Research Area|Immunology & Inflammation|Arthritis (Non-autoimmune)||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Leukotrienes||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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