A pyrazine derivative that is used as a flavoring agent in the food and tobacco industry; has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50 = ~1.25 mM)

2,5-Deoxyfructosazine (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
17460-13-8
Storage:
-20
UN-No:
Non-Hazardous - /

2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry.{30119,30120} Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia.{30120} 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH.{30123,30121} Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50 = ~1.25 mM).{30122,30121,30123}  

 

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Description

A pyrazine derivative that is used as a flavoring agent in the food and tobacco industry; has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50 = ~1.25 mM)

Formal name: (1R,2S,3R) 1-[5-[(2S,3R)-2,3,4-trihydroxybutyl]-2-pyrazinyl]-1,2,3,4-butanetetrol, dihydrochloride

Synonyms:  NSC 270912

Molecular weight: 377.2

CAS: 17460-13-8

Purity: ≥98%

Formulation: Acrystalline solid

Product Type|Biochemicals|Natural Products||Research Area|Immunology & Inflammation

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