A phytosterol that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism; demonstrates beneficial cardiovascular effects by reducing cholesterol for lowering the incidence of atherosclerotic plaques and anticancer effects by activating LXR signaling

24α-methyl Cholesterol – 5 mg

Brand:
Cayman
CAS:
474-62-4
Storage:
-20
UN-No:
Non-Hazardous - /

24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism.{28271} The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques.{20083} 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.{15405}  

 

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Description

A phytosterol that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism; demonstrates beneficial cardiovascular effects by reducing cholesterol for lowering the incidence of atherosclerotic plaques and anticancer effects by activating LXR signaling

Formal name: (3β,24R)-ergost-5-en-3-ol

Synonyms:  Campesterol|NSC 224330

Molecular weight: 400.7

CAS: 474-62-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Natural Products|Phytosterols||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cancer||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Cardiovascular System|Lipids & Lipoproteins|Cholesterol Metabolism||Research Area|Endocrinology & Metabolism|Hormones & Receptors|FXRs & LXRs||Research Area|Lipid Biochemistry|Sterol Lipids||Research Area|Plant Biology

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