An oxidation product of DHA; formed by human CYP4F3B in BTI-TN-5B1-4 microsomes; serum levels increase in humans following dietary DHA supplementation

22-HDHA – 100 µg

Brand:
Cayman
CAS:
90780-46-4
Storage:
-20
UN-No:
Non-Hazardous - 1231 / 3

22-HDHA is an oxidation product of docosahexaenoic acid (DHA; Item No. 90310).{7480} In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes.{7480,37628} Serum levels of 22-HDHA increase following dietary DHA supplementation in humans.{29249}  

 

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Description

An oxidation product of DHA; formed by human CYP4F3B in BTI-TN-5B1-4 microsomes; serum levels increase in humans following dietary DHA supplementation

Formal name: 22-hydroxy-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid

Synonyms:  22-hydroxy Docosahexaenoic Acid|22-OH DHA

Molecular weight: 344.5

CAS: 90780-46-4

Purity: ≥95%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Docosanoids||Research Area|Lipid Biochemistry|Fatty Acids||Research Area|Lipid Biochemistry|Reactive O2/N2 Pathways||Research Area|Neuroscience||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation

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