A natural steroid glycoside with diverse effects; inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a concentration of 25 mg/kg; inhibits growth of HRA ovarian and Bxpc-3 pancreatic cancer cells in a dose-dependent manner; decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma; reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury

20(S)-Ginsenoside Rh2 – 1 mg

Brand:
Cayman
CAS:
78214-33-2
Storage:
-20
UN-No:
Non-Hazardous - /

Ginsenoside Rh2 is a steroid glycoside found in plants of the genus Panax that has diverse biological activities.{40327,40328,40329,40330,40331} It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg.{40327} It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner.{40329,40330} In vivo, ginsenoside Rh2 decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma.{40331} Ginsenoside Rh2 also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.{40328}  

 

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Description

A natural steroid glycoside with diverse effects; inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a concentration of 25 mg/kg; inhibits growth of HRA ovarian and Bxpc-3 pancreatic cancer cells in a dose-dependent manner; decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma; reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury

Formal name: 12β,20-dihydroxydammar-24-en-3β-yl, β-D-glucopyranoside

Synonyms:  20(S)-Ginsenoside Rh2

Molecular weight: 622.9

CAS: 78214-33-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Natural Products|Glycosides||Research Area|Cancer||Research Area|Immunology & Inflammation|Allergy||Research Area|Neuroscience|Behavioral Neuroscience|Depression||Research Area|Neuroscience|Neuroprotection|Ischemia

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