An ecdysteroid hormone produced in arthropod species that induces developmental changes associated with ecdysis and the completion of metamorphosis; used as a tool in inducible gene regulation systems controlled by reporter cells transfected with the ecdysone receptor

20-hydroxy Ecdysone – 10 mg

Brand:
Cayman
CAS:
5289-74-7
Storage:
-20
UN-No:
Non-Hazardous - /

20-hydroxy Ecdysone is an ecdysteroid hormone produced in arthropod species that induces developmental changes associated with ecdysis and the completion of metamorphosis.{26314} It is also produced in plants as a defensive strategy to disrupt the development of insect pests.{26312} In target tissues, 20-hydroxy ecdysone binds to the nuclear hormone receptor, ecdysone receptor, initiating a signaling cascade that results in cell cycle arrest.{26314,26313} Ecdysteroids such as this compound have been employed as tools in inducible gene regulation systems controlled by reporter cells transfected with the ecdysone receptor.{26316,26315}  

 

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Description

An ecdysteroid hormone produced in arthropod species that induces developmental changes associated with ecdysis and the completion of metamorphosis; used as a tool in inducible gene regulation systems controlled by reporter cells transfected with the ecdysone receptor

Formal name: (5β)-2β,3β,14,20,22R,25-hexahydroxy-cholest-7-en-6-one

Synonyms:  Ecdysterone|Isoinokosterone

Molecular weight: 480.6

CAS: 5289-74-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cell Biology|Cell Cycle||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Plant Biology

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