A natural monoacylglycerol that is metabolized by monoacylglycerol lipase; an agonist of GPR119 (EC50 = 2.5 µM)

2-Oleoyl Glycerol – 10 mg

Brand:
Cayman
CAS:
3443-84-3
Storage:
-80
UN-No:
De Minimis - 1170 / 3

2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol (2-AG; Item No. 62160), is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases.{15412,14196,27758} 2-OG is an agonist of GPR119 (EC50 = 2.5 µM), stimulating the release of glucagon-like peptide-1 from intestinal L-cells.{27759}  

 

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Description

A natural monoacylglycerol that is metabolized by monoacylglycerol lipase; an agonist of GPR119 (EC50 = 2.5 µM), stimulating the release of glucagon-like peptide-1 from intestinal L-cells

Formal name: 2-hydroxy-1-(hydroxymethyl)ethyl ester-9Z-octadecenoic acid

Synonyms:  2-Monoolein|2-OG

Molecular weight: 356.5

CAS: 3443-84-3

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Glycerolipids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Lipid Biochemistry|Glycerolipids

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