A synthetic PAF analog which contains an ether-linked methyl group at the sn-2 position; decreases plasma membrane fluidity

2-O-methyl PAF C-18 – 10 mg

Brand:
Cayman
CAS:
77286-66-9
Storage:
-20
UN-No:
Non-Hazardous - /

2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.{2099} In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase.{2985}  

 

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SKU: 60912 - 10 mg Category:

Description

A synthetic PAF analog which contains an ether-linked methyl group at the sn-2 position; decreases plasma membrane fluidity, inhibits tumor cell invasiveness, and causes the release of large quantities of NO by a pathway involving activation of NOS

Formal name: 3,5,9-trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7R-methoxy-N,N,N-trimethyl-4-oxide

Synonyms:  1-O-octadecyl-2-O-methyl-sn-glyceryl-3-phosphorylcholine|Edelfosine|ET-18-OCH3

Molecular weight: 523.7

CAS: 77286-66-9

Purity: ≥98%

Formulation: A lyophilized powder

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