2-O-Acetyl-20-hydroxyecdysone – 1 mg

Brand:
Cayman
CAS:
19536-25-5
Storage:
-20
UN-No:
Non-Hazardous - /

2-O-Acetyl-20-hydroxyecdysone is an ecdysone steroid hormone that has been found in plants and animals.{46337} It completely inhibits the growth of the bacteria S. aureus, E. coli, and P. vulgaris, as well as the fungi C. albicans, A. alternata, and F. solani when used at a concentration of 10 µg/ml. 2-O-Acetyl-20-hydroxyecdysone (50 µM) increases aggregation of amyloid-β (1-42) (Aβ42), increases fibril formation by 60%, and decreases oligomer levels in cell-free assays.{46338} It reduces Aβ42-induced cytotoxicity of SH-SY5Y cells when used at concentrations of 5 and 10 µM.  

 

Available on backorder

SKU: 28063 - 1 mg Category:

Description

An ecdysone steroid hormone; completely inhibits the growth of the bacteria S. aureus, E. coli, and P. vulgaris, as well as the fungi C. albicans, A. alternata, and F. solani at 10 µg/ml; increases aggregation of Aβ42, increases fibril formation by 60%, and decreases oligomer levels in cell-free assays at 50 µM; reduces Aβ42-induced cytotoxicity of SH-SY5Y cells at 5 and 10 µM


Formal name: (2β,3β,5β,22R)-2-(acetyloxy)-3,14,20,22,25-pentahydroxy-cholest-7-en-6-one

Synonyms:  β-Ecdysone 2-acetate

Molecular weight: 522.7

CAS: 19536-25-5

Purity: ≥95%

Formulation: A solid


Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Natural Products||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Fungal Diseases|Candidiasis||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease