A hydroxy fatty acid; a partial agonist of FFAR1/GPR40 and GPR85 receptors in vitro (EC50s = 6.7 and 12.8 μM

2-hydroxy Lauric Acid – 10 mg

Brand:
Cayman
CAS:
2984-55-6
Storage:
-20
UN-No:
Non-Hazardous - /

2-hydroxy Lauric acid is a naturally occuring hydroxylated fatty acid that is found in Acinetobacter species.{36605} It acts as a partial agonist of free fatty acid receptor 1 (FFAR1/GPR40) and GPR84 receptors in vitro (EC50s = 6.7 and 12.8 μM, respectively).{40827} 2-hydroxy Lauric acid also inhibits bovine hepatic ligase (Ki = 4.4 μM) and mouse kidney mitochondrial medium-chain acyl-CoA synthetase by 48% at a concentration of 40 μM.{24586} [Matreya, LLC. Catalog No. 1701]  

 

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Description

A hydroxy fatty acid; a partial agonist of FFAR1/GPR40 and GPR85 receptors in vitro (EC50s = 6.7 and 12.8 μM, respectively); inhibits bovine hepatic ligase (Ki = 4.4 μM); inhibits medium-chain acyl-CoA synthetase by 48% in mouse kidney mitochondria (40 μM)

Formal name: 2-hydroxy-dodecanoic acid

Synonyms:  (±)-2-hydroxy Dodecanoic Acid|(±)-α-hydroxy Dodecanoic Acid|(±)-α-hydroxy Lauric Acid|NSC 39025

Molecular weight: 216.3

CAS: 2984-55-6

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Fatty Acids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Lipid Biochemistry

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