A purine nucleoside with diverse biological activities; inhibits the clonogenic growth of HL-60 and K562 leukemia cells (IC50s = 80 and 100 µM

2′-Deoxyguanosine – 5 g

Brand:
Cayman
CAS:
961-07-9
Storage:
-20
UN-No:
Non-Hazardous - /

2′-Deoxyguanosine is a purine nucleoside with diverse biological activities.{53664,53663,53662,53665} It inhibits the clonogenic growth of HL-60 and K562 leukemia cells (IC50s = 80 and 100 µM, respectively).{53664} 2′-Deoxyguanosine inhibits the growth of MOLT-4 T cells and MGL-8 B cells by 99.8 and 68.3%, respectively, when used at a concentration of 50 µM.{53663} It increases the number of binucleated cells, a marker of inhibited cytokinesis, in A. sativum meristems.{53662} 2′-Deoxyguanosine (>1 µM) also induces relaxation of precontracted isolated bovine lingual artery.{53665}  

 

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SKU: 9002864 - 5 g Category:

Description

A purine nucleoside with diverse biological activities; inhibits the clonogenic growth of HL-60 and K562 leukemia cells (IC50s = 80 and 100 µM, respectively); inhibits the growth of MOLT-4 T cells and MGL-8 B cells at 50 µM; increases the number of binucleated cells in A. sativum meristems; induces relaxation of precontracted isolated bovine lingual artery at >1 µM

Formal name: 2′-deoxy-guanosine

Synonyms:  Guanine deoxyriboside|NSC 22837

Molecular weight: 267.2

CAS: 961-07-9

Purity: ≥98%

Formulation: A solid

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