2-chloro-3-Deazaadenosine – 5 mg

Brand:
Cayman
CAS:
40656-71-1
Storage:
-20
UN-No:
Non-Hazardous - /

Adenosine receptors are a family of G protein-coupled receptors that display distinct patterns of ligand binding and tissue distribution, regulating a variety of physiological functions. 2-chloro-3-Deazaadenosine is a stable analog of adenosine that acts as an agonist for adenosine receptors (Ki = 0.3, 0.08, 25.5, and 1.9 μM for A1, A2A, A2B, and A3 receptors, respectively).{19450,19451} It can block neurotransmitter release by activating A1 receptors or inhibit neurotransmission by activating A2A receptors.{19446,19453,19448} 2-chloro-3-Deazaadenosine blocks seizures by stimulating A1 receptors.{19449,19452}  

 

Available on backorder

SKU: 9000787 - 5 mg Category:

Description

A stable analog of adenosine that acts as an agonist for adenosine receptors (Ki = 0.3, 0.08, 25.5, and 1.9 μM for A1, A2A, A2B, and A3 receptors, respectively); modulates neurotransmission release and blocks seizures by activating adenosine receptors


Formal name: 6-chloro-1-β-D-ribofuranosyl-1H-imidazo[4,5-c]pyridin-4-amine

Synonyms:  2-CADO|6-Amino-2-chloropurine riboside|NSC 158900

Molecular weight: 300.7

CAS: 40656-71-1

Purity: ≥98%

Formulation: A crystalline solid