Description
A cell-permeable antagonist of IP3 receptors
Formal name: 2,2-diphenyl-1,3,2-oxaza-borolidine internal salt
Synonyms:
Molecular weight: 225.1
CAS: 524-95-8
Purity: ≥98%
Formulation: A crystalline solid
2-Aminoethyl diphenylborinate – 5 g
Brand:
Cayman
CAS:
524-95-8
Storage:
-20
UN-No:
Non-Hazardous - /
Receptor-induced calcium signalling relies on inositol-1,4,5-triphosphate receptors.{11002} These receptors can be blocked by the cell-permeable antagonist 2-aminoethyl diphenylborinate. In fura-loaded DDT1MF-2 cells, 75 µM 2-aminoethyl diphenylborinate completely ablates the thapsigargin-induced calcium transients that are also antagonized by xestospongin C.{9842}
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