A major CYP450 metabolite of arachidonic acid that is released from the kidney in response to angiotensin II; a potent vasodilator of renal preglomerular vessels

19(S)-HETE – 50 µg

Brand:
Cayman
CAS:
115461-40-0
Storage:
-20
UN-No:
De Minimis - 1170 / 3

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively.{15766} Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels.{3825} 19(S)-HETE stimulates both renal sodium-potassium ATPase and volume absorption in the rabbit proximal straight tubule.{254,18012}  

 

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SKU: 10007766 - 50 µg Category:

Description

A major CYP450 metabolite of arachidonic acid that is released from the kidney in response to angiotensin II; a potent vasodilator of renal preglomerular vessels

Formal name: 19S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid

Synonyms: 

Molecular weight: 320.5

CAS: 115461-40-0

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Hydroxy/Hydroperoxy/ Epoxy/Oxo Eicosanoids||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Vasculature||Research Area|Lipid Biochemistry|Cytochrome P450 Pathways

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