A fungal metabolite; inhibits the growth of chloroquine-sensitive and -resistant strains of P. falciparum (IC50s = 0.07 and 0.05 ng/ml

19,20-Epoxycytochalasin C – 1 mg

Brand:
Cayman
CAS:
189351-79-9
Storage:
-20
UN-No:
Non-Hazardous - /

19,20-Epoxycytochalasin C is a fungal metabolite originally isolated from Nemania sp. UM10M.{46279} It inhibits the growth of chloroquine-sensitive and -resistant strains of P. falciparum (IC50s = 0.07 and 0.05 ng/ml, respectively) without inducing cytotoxicity in Vero cells (IC50 = >4,760 ng/ml). 19,20-Epoxycytochalasin C is also phytotoxic, reducing growth of lettuce and bentgrass plants when used at a concentration of 1 mg/ml.  

 

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SKU: 28025 - 1 mg Category:

Description

A fungal metabolite; inhibits the growth of chloroquine-sensitive and -resistant strains of P. falciparum (IC50s = 0.07 and 0.05 ng/ml, respectively); reduces growth of lettuce and bentgrass plants at 1 mg/ml

Formal name: (3S,3aR,4E,7S,9R,9aR,10aS,11S,11aR,14S,14aR)-11-(acetyloxy)-6,7,9,9a,10a,11,14,14a-octahydro-3,9-dihydroxy-1,2,7,9-tetramethyl-14-(phenylmethyl)-3H-oxireno[9,10]cycloundec[1,2-d]isoindole-8,12(3aH,13H)-dione

Synonyms: 

Molecular weight: 523.6

CAS: 189351-79-9

Purity: ≥95%

Formulation: A powder

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Malaria||Research Area|Plant Biology|Phytotoxins||Research Area|Plant Biology|Plant Growth Regulators

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