A minorCYP450 metabolite of arachidonic acid that potently inhibits proximal tubule ATPase activity

17(S)-HETE – 100 µg

Brand:
Cayman
CAS:
183509-25-3
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney.17(S)-HETE inhibits proximal tubule ATPase activity by as much as 70% at a concentration of 2 µM.{3825}  

 

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SKU: 10011305 - 100 µg Category:

Description

A minorCYP450 metabolite of arachidonic acid that potently inhibits proximal tubule ATPase activity

Formal name: 17S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid

Synonyms: 

Molecular weight: 320.5

CAS: 183509-25-3

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Hydroxy/Hydroperoxy/ Epoxy/Oxo Eicosanoids||Product Type|Biochemicals|Small Molecule Inhibitors|ATPases||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Lipid Biochemistry|Cytochrome P450 Pathways

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