The primary oxygenation product of DHA when exposed to aspirin-inhibited COX-2; serves as a precursor to resolvins and has intrinsic biological activity

17(R)-HDHA – 25 µg

Brand:
Cayman
CAS:
155976-53-7
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Resolvins are a group of polyhydroxylated metabolites of docosahexaenoic acid (DHA) found in the inflammatory exudates of aspirin-treated experimental animals.{11433} 17(R)-HDHA is the primary oxygenation product of DHA when exposed to aspirin-inhibited cyclooxygenase-2. 17(R)-HDHA serves as a precursor to resolvins and has intrinsic biological activity, such as the inhibition of TNFα-induced IL-1β expression in human glioma cells.{11433}  

 

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SKU: 10005099 - 25 µg Category:

Description

The primary oxygenation product of DHA when exposed to aspirin-inhibited COX-2; serves as a precursor to resolvins and has intrinsic biological activity, such as the inhibition of TNF-α-induced IL-1β expression in human glioma cells

Formal name: 17R-hydroxy-4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid

Synonyms:  17(R)-HDoHE|17(R)-hydroxy Docosahexaenoic Acid

Molecular weight: 344.5

CAS: 155976-53-7

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Docosanoids||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Specialized Pro-Resolving Mediators||Research Area|Lipid Biochemistry|Reactive O2/N2 Pathways||Research Area|Neuroscience

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