17-hydroxy Heptadecanoic acid is a hydroxylated fatty acid that has been found in aeolian particles collected on the Frioul Islands and in the outer bark of E. globulus.{38891,38892} It has been used in the synthesis of various macrocyclic lactones.{38893} [Matreya, LLC. Catalog No. 1760]
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A hydroxylated fatty acid; has been found in aeolian particles collected on the Frioul Islands and in the outer bark of E. globulus; has been used in the synthesis of various macrocyclic lactones,,
Formal name: 17-hydroxy-heptadecanoic acid
Synonyms: ω-hydroxy Heptadecanoic Acid
Molecular weight: 286.5
CAS: 13099-34-8
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Lipids|Fatty Acids||Research Area|Lipid Biochemistry|Fatty Acids
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The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 µM compared to 20 µM by resveratrol.{14545}
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