A minor CYP450 metabolite of arachidonic acid that potently inhibits proximal tubule ATPase activity

16(S)-HETE – 50 µg

Brand:
Cayman
CAS:
183509-23-1
Storage:
-20
UN-No:
Non-Hazardous - 1170 / 3

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase activity by as much as 60% at a concentration of 2 µM.{3825}  

 

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SKU: 10004384 - 50 µg Category:

Description

A minor CYP450 metabolite of arachidonic acid that potently inhibits proximal tubule ATPase activity

Formal name: 16S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid

Synonyms: 

Molecular weight: 320.5

CAS: 183509-23-1

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Hydroxy/Hydroperoxy/ Epoxy/Oxo Eicosanoids||Product Type|Biochemicals|Small Molecule Inhibitors|ATPases||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Lipid Biochemistry|Cytochrome P450 Pathways

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