Description
A PDI inhibitor; inhibits PDI reductase activity in an enzyme assay from 1-100 µg/ml; reduces HTTQ103-induced PC12 cell apoptosis; suppresses PDI-dependent MOMP in isolated PC12 mitochondria; reduces HTTN90Q73 mutant huntingtin-induced medium spinal neuron death and MOMP in rat corticostriatal slices at 2, 3, 4, and 10 µM; reduces APP-induced pyramidal neuron death in rat corticostriatal slices
Formal name: 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-methyl-1H-pyrido[3,4-b]indole-1-carboxylic acid, methyl ester
Synonyms:
Molecular weight: 320.8
CAS: 922507-80-0
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease||Research Area|Neuroscience|Neurodegenerative Disorders|Huntington’s Disease