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16,16-dimethyl Prostaglandin A2 – 10 mg

Brand:
Cayman
CAS:
41691-92-3
Storage:
-20
UN-No:
De Minimis - 1231 / 3

16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 µg/ml.{2680} Daily infusion of 10 µg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%.{1136} Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time.{1184}  

 

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SKU: 10280 - 10 mg Category:

Description

16,16-dimethyl PGA2 is a metabolism resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 µg/ml.{2680} Daily infusion of 10 µg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%.{1136} Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time.{1184}

Formal name: 9-oxo-15R-hydroxy-16,16-dimethyl-prosta-5Z,10,13E-trien-1-oic acid

Synonyms:  16,16-dimethyl PGA2

Molecular weight: 362.5

CAS: 41691-92-3

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Cancer||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|Influenza||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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