A metabolism resistant analog of PGA1

16,16-dimethyl Prostaglandin A1 – 1 mg

Brand:
Cayman
CAS:
41692-24-4
Storage:
-20
UN-No:
De Minimis - 1231 / 3

16,16-dimethyl PGA1 is a metabolism resistant analog of PGA1. In vitro, it inhibits the viral replication in both HSV and HIV-1 infection systems at concentrations that do not adversely alter cellular DNA synthesis. The ID50 for HSV-1 strains in Vero cells and human foreskin fibroblasts are 3.8-5.6 µg/ml and 4.6-7.3 µg/ml, respectively. The ID50 for T cells acutely infected with HIV-1 is 2.5 µg/ml.{811}  

 

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SKU: 10080 - 1 mg Category:

Description

A metabolism resistant analog of PGA1

Formal name: 9-oxo-15R-hydroxy-16,16-dimethyl-prosta-10,13E-dien-1-oic acid

Synonyms:  16,16-dimethyl PGA1

Molecular weight: 364.5

CAS: 41692-24-4

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS||Research Area|Infectious Disease|Viral Diseases|HSV||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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