A lipophilic analog of 16-phenoxy tetranor PGF2α

16-phenoxy tetranor Prostaglandin F2α methyl ester – 5 mg

Brand:
Cayman
CAS:
51638-90-5
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.{2058} 16-phenoxy tetranor PGF2α methyl ester is a lipophilic analog of 16-phenoxy tetranor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.  

 

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SKU: 10010102 - 5 mg Category:

Description

A lipophilic analog of 16-phenoxy tetranor PGF2α

Formal name: 9α,11α,15R-trihydroxy-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, methyl ester

Synonyms:  16-phenoxy tetranor PGF2α

Molecular weight: 404.5

CAS: 51638-90-5

Purity: >98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology

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