15(R)-PGF2α is the C-15 epimer of the naturally occurring mammalian autacoid PGF2α. It has only 25% of the potency of PGF2α in hamster antifertility studies

15(R)-Prostaglandin F2α – 10 mg

Brand:
Cayman
CAS:
37658-84-7
Storage:
-20
UN-No:
De Minimis - 1231 / 3

15(R)-PGF2α is the C-15 epimer of the naturally occurring mammalian autacoid PGF2α. It has only 25% of the potency of PGF2α in hamster antifertility studies,{1925} which may be due to reduced affinity for FP receptors. Compared to PGF2α, 15(R)-PGF2α has a binding affinity of 6.7% to ovine luteal cell receptors.{2058} Similarly, the binding affinity to rat vascular smooth muscle cells is negligible as compared to PGF2α.{2057}  

 

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15(R)-PGF2α is the C-15 epimer of the naturally occurring mammalian autacoid PGF2α. It has only 25% of the potency of PGF2α in hamster antifertility studies,{1925} which may be due to reduced affinity for FP receptors. Compared to PGF2α, 15(R)-PGF2α has a binding affinity of 6.7% to ovine luteal cell receptors.{2058} Similarly, the binding affinity to rat vascular smooth muscle cells is negligible as compared to PGF2α.{2057}

Formal name: 9α,11α,15R-trihydroxy-prosta-5Z,13E-dien-1-oic acid

Synonyms:  15-epi PGF2α

Molecular weight: 354.5

CAS: 37658-84-7

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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