Description
An HIV-1 integrase inhibitor and free radical scavenger; inhibits HIV-1 integrase 3′ end processing, end joining, and disintegration (IC50s = 0.35, 0.56, and 0.84 μg/ml, respectively); inhibits HIV-1 replication in MT-2 cells (ED50 = 2 μg/ml); dose-dependently reduces the level of free radicals released by FMLP stimulation of PMN cells at 0.25-1 μM; dose-dependently increases cell survival and GSH levels and decreases ROS and LDH release when rat cerebral astrocytes in an oxygen-glucose deprivation/reperfusion assay using rat cerebral astrocytes at 5-100 μM
Formal name: (1S,3R,4R,5R)-1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-cyclohexanecarboxylic acid
Synonyms: 1,3-Dicaffeoylquinic Acid|1,5-DCQA
Molecular weight: 516.5
CAS: 19870-46-3
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Antivirals|Integrase Inhibitors||Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Sulfur|Glutathione
