15-deoxy-Δ12,14-Prostaglandin J2 MaxSpec® Standard – 100 µg

Brand:
Cayman
CAS:
87893-55-8
Storage:
-20
UN-No:
De Minimis - 1231 / 3

15-deoxy-Δ12,14-Prostaglandin J2 (15-deoxy-Δ12,14-PGJ2) is formed from PGD2 (Item Nos. 12010 | 10007202) by the elimination of two molecules of water. It binds selectively to PPARγ with an EC50 value of 2 µM in a murine chimera system.{1428,1424} 15-deoxy-Δ12,14-PGJ2 is more potent than PGD2, Δ12-PGJ2 (Item Nos. 18550 | 10007234), and PGJ2 (Item Nos. 18500 | 10007233) in stimulating lipogenesis in C3H10T1/2 cells. The EC50 value for induction of adipocyte differentiation in cultured fibroblasts is 7 µM.{1428} 15-deoxy-Δ12,14-PGJ2 MaxSpec® standard is a quantitative grade standard of 15-deoxy-Δ12,14-PGJ2 (Item No. 18570) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 15-deoxy-Δ12,14-PGJ2 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.  

 

Available on backorder

SKU: 10007235 - 100 µg Category:

Description

A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications,


Formal name: 11-oxo-prosta-5Z,9,12E,14Z-tetraen-1-oic acid

Synonyms:  15-deoxy-Δ12,14-PGJ2

Molecular weight: 316.4

CAS: 87893-55-8

Purity: ≥95%

Formulation: A solution in methyl acetate at 100 µg/ml


Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards|MaxSpec®||Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway