13(S)-HpODE is produced by the oxidation of linoleic acid by LO-1 in many plants including soybean

13(S)-HpODE – 1 mg

Brand:
Cayman
CAS:
33964-75-9
Storage:
-80
UN-No:
Excepted Quantity - 1170 / 3

13(S)-HpODE is produced by the oxidation of linoleic acid by lipoxygenase-1 (LO-1) in many plants including soybean, flaxseed, apples, and tea leaves,{123,770} and by 15-LO in mammals.{4193} In plants, 13(S)-HpODE is the preferred substrate for the garlic bulb divinyl ether synthase.{3824} In mammalian tissues, 13(S)-HpODE is generally reduced to 13(S)-HODE (Catalog No. 38610), a compound which exhibits many biological activities.{4193} A direct action for 13(S)-HpODE has been demonstrated in Syrian hamster embryo cells where it stimulates EGF-dependent mitogenesis and up-regulation of EGF-dependent tyrosine phosphorylation.{4902} Membrane-esterified 13(S)-HpODE has been identified in human atherosclerotic plaques.{2406}  

 

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Description

13(S)-HpODE is produced by the oxidation of linoleic acid by LO-1 in many plants including soybean, flaxseed, apples, and tea leaves,{123,770} and by 15-LO in mammals.{4193} In plants, 13(S)-HpODE is the preferred substrate for the garlic bulb divinyl ether synthase.{3824} In mammalian tissues, 13(S)-HpODE is generally reduced to 13(S)-HODE, a compound which exhibits many biological activities.{4193} A direct action for 13(S)-HpODE has been demonstrated in Syrian hamster embryo cells where it stimulates EGF-dependent mitogenesis and up-regulation of EGF-dependent tyrosine phosphorylation.{4902} Membrane-esterified 13(S)-HpODE has been identified in human atherosclerotic plaques.{2406}

Formal name: 13S-hydroperoxy-9Z,11E-octadecadienoic acid

Synonyms: 

Molecular weight: 312.4

CAS: 33964-75-9

Purity: ≥95%

Formulation: A solution in ethanol

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