A polyphenol; decreases the expression and protein levels of iNOS at 10 µM in HCASMCs treated with a cytokine mixture; decreases protein levels of tyrosinase and MITF in B16F1 cells; inhibits melanogenesis in B16F1 cells and decreases tyrosinase activity in cell lysates at 25 µM; reduces triglyceride levels in sodium oleate-induced hyperlipidemic HepG2 cells at 20 and 40 µM

1,3-Dicaffeoylquinic Acid – 5 mg

Brand:
Cayman
CAS:
30964-13-7
Storage:
-20
UN-No:
Non-Hazardous - /

1,3-Dicaffeoylquinic acid is a polyphenol that has been found in C. scolymus.{47054} It decreases the expression and protein levels of inducible nitric oxide synthase (iNOS) when used at a concentration of 10 µM in human coronary artery smooth muscle cells (HCASMCs) treated with a cytokine mixture.{47055} 1,3-Dicaffeoylquinic acid decreases protein levels of tyrosinase and microphthalmia-associated transcription factor (MITF) in B16F1 murine melanocytes.{47056} It inhibits melanogenesis in B16F1 cells and decreases tyrosinase activity in cell lysates when used at a concentration of 25 µM.{47054} 1,3-Dicaffeoylquinic acid (20 and 40 µM) reduces triglyceride levels in sodium oleate-induced hyperlipidemic HepG2 cells compared to hyperlipidemic control cells.  

 

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SKU: 25022 - 5 mg Category:

Description

A polyphenol; decreases the expression and protein levels of iNOS at 10 µM in HCASMCs treated with a cytokine mixture; decreases protein levels of tyrosinase and MITF in B16F1 cells; inhibits melanogenesis in B16F1 cells and decreases tyrosinase activity in cell lysates at 25 µM; reduces triglyceride levels in sodium oleate-induced hyperlipidemic HepG2 cells at 20 and 40 µM

Formal name: (1R,3R,4S)-1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5R-dihydroxy-cyclohexanecarboxylic acid

Synonyms:  Cynarin

Molecular weight: 516.5

CAS: 30964-13-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Polyphenols||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cardiovascular System|Vasculature|Smooth Muscle Cells||Research Area|Lipid Biochemistry|Glycerolipids

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