A phospholipid; SapC-DOPS nanovesicles are cytotoxic to SK-MEL-28 cells in vitro and decrease tumor volume in a squamous cell carcinoma mouse xenograft model; has been used in the formation of unilamellar vesicles to study the effect of curvature on membrane structure and in the formation of supported lipid bilayers to study the effects of various support materials on lipid redistribution between membrane leaflets

1,2-Dioleoyl-sn-glycero-3-PS (sodium salt) – 5 mg

Brand:
Cayman
CAS:
90693-88-2
Storage:
-20
UN-No:
Non-Hazardous - /

1,2-Dioleoyl-sn-glycero-3-PS (DOPS) is a phospholipid containing oleic acid (Item Nos. 90260 | 24659) at the sn-1 and sn-2 positions, respectively. Nanovesicles composed of DOPS and the lysosomal protein saposin C (SapC) are cytotoxic to SK-MEL-28 cells in vitro and decrease tumor volume in a squamous cell carcinoma mouse xenograft model.{46817} DOPS has been used in the formation of unilamellar vesicles to study the effect of curvature on membrane structure and in the formation of supported lipid bilayers to study the effects of various support materials on lipid redistribution between membrane leaflets.{46818,46819}  

 

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SKU: 29983 - 5 mg Category:

Description

A phospholipid; SapC-DOPS nanovesicles are cytotoxic to SK-MEL-28 cells in vitro and decrease tumor volume in a squamous cell carcinoma mouse xenograft model; has been used in the formation of unilamellar vesicles to study the effect of curvature on membrane structure and in the formation of supported lipid bilayers to study the effects of various support materials on lipid redistribution between membrane leaflets

Formal name: (2S,8R,19Z)-2-amino-5-hydroxy-11-oxo-8-[[(9Z)-1-oxo-9-octadecenyl]oxy]-4,6,10-trioxa-5-phosphaoctacos-19-enoic acid, 5-oxide, monosodium salt

Synonyms:  1,2-Dioctadecenoyl-sn-glycero-3-Phosphatidylserine|1,2-Dioctadecenoyl-sn-glycero-3-Phosphoserine|18:1/18:1-PS; PS(18:1/18:1)|DOPS

Molecular weight: 810

CAS: 90693-88-2

Purity: ≥95%

Formulation: A crystalline solid

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