A synthetic phosphatidylcholine; contains containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions; commonly used in the formation of lipid bilayers and mixed micelles (CMC = 1.6 mM); increases the formation rate of substrate-supported planar phospholipid bilayers on glass and silica; inhibits insulin fibril formation in vitro in a concentration-dependent manner; inhibits cytotoxicity induced by insulin fibril formation in PC12 and SH-SY5Y cells at 0.5-4 mM

1,2-Diheptanoyl-sn-glycero-3-PC – 100 mg

Brand:
Cayman
CAS:
39036-04-9
Storage:
-20
UN-No:
Non-Hazardous - /

1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions. It is commonly used in the formation of lipid bilayers and mixed micelles that has a critical micelle concentration (CMC) of 1.6 mM.{41970,41971} Short-chain phospholipids, such as DHPC-C7 and 1,2-dihexanoyl-sn-glycero-PC (DHPC-C6; Item No. 25585), increase the formation rate of substrate-supported planar phospholipid bilayers on glass and silica.{41971} DHPC-C7 inhibits insulin fibril formation in vitro in a concentration-dependent manner and inhibits cytotoxicity induced by insulin fibril formation in PC12 and SH-SY5Y cells when used at concentrations ranging from 0.5 to 4 mM.{41972}  

 

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SKU: 25586 - 100 mg Category:

Description

A synthetic phosphatidylcholine; contains containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions; commonly used in the formation of lipid bilayers and mixed micelles (CMC = 1.6 mM); increases the formation rate of substrate-supported planar phospholipid bilayers on glass and silica; inhibits insulin fibril formation in vitro in a concentration-dependent manner; inhibits cytotoxicity induced by insulin fibril formation in PC12 and SH-SY5Y cells at 0.5-4 mM

Formal name: (7R)-4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxoheptyl)oxy]-3,5,9-trioxa-4-phosphahexadecan-1-aminium, inner salt, 4-oxide

Synonyms:  DHPC-C7|di-C7-PC

Molecular weight: 481.6

CAS: 39036-04-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Glycerophospholipids||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Lipid Biochemistry|Glycerophospholipids

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