A withanolide; has anti-inflammatory activity

12-Deoxywithastramonolide – 5 mg

Brand:
Cayman
CAS:
60124-17-6
Storage:
-20
UN-No:
Non-Hazardous - /

12-Deoxywithastramonolide is a withanolide found in W. somnifera roots.{37258} It has anti-inflammatory activity, reducing Tnf-α and increasing Il-10 production in mice following oral administration at doses ranging from 50-200 mg/kg. 12-Deoxywithastramonolide also reduces the growth of A549 lung and HT-29 colorectal cancer cells (IC50s = 47.1 and 29.8 μM, respectively).{37259}  

 

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SKU: 11669 - 5 mg Category:

Description

A withanolide; has anti-inflammatory activity, reducing Tnf-α and increasing Il-10 production in mice following oral administration at doses ranging from 50-200 mg/kg; reduces the growth of A549 lung and HT-29 colorectal cancer cells (IC50s = 47.1 and 29.8 μM, respectively)

Formal name: 6α,7α-epoxy-5α,22R,27-trihydroxy-1-oxo-ergosta-2,24-dien-26-oic acid δ-lactone

Synonyms:  27-Hydroxywithanolide B|Baimantuoluoside C aglycone

Molecular weight: 470.6

CAS: 60124-17-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Research Area|Cancer||Research Area|Immunology & Inflammation

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