11-trans LTD4 is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum

11-trans Leukotriene D4 – 25 µg

Brand:
Cayman
CAS:
79768-40-4
Storage:
-20
UN-No:
De Minimis - 1170 / 3

11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4.{11179,11181} It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.{11181,11178}  

 

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Description

11-trans LTD4 is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4.{11179,11181} It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.{11181,11178}

Formal name: 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E,14Z-eicosatetraenoic acid

Synonyms:  11-trans LTD4

Molecular weight: 496.7

CAS: 79768-40-4

Purity: ≥97%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Leukotrienes||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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