One of the main metabolites of TXB2; can be used as a marker of in vivo TXA2 synthesis; urinary concentrations of 11-TXB2 are approximately 30-70 ng/mmol creatinine

11-dehydro Thromboxane B2 – 250 µg

Brand:
Cayman
CAS:
67910-12-7
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.{1410} 11-dehydro TXB2 is one of the main plasma metabolites of TXB2 and can be used as a marker for in vivo TXA2 synthesis.{1410,438,278,518} The mean plasma level in human males is 0.9-4.3 pg/ml and the half life is 45-60 minutes.{438,278,518} Urinary concentrations of 11-dehydro TXB2 are approximately 30-70 ng/mmol creatinine.{6109,7635}  

 

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Description

One of the main metabolites of TXB2; can be used as a marker of in vivo TXA2 synthesis; urinary concentrations of 11-TXB2 are approximately 30-70 ng/mmol creatinine,

Formal name: 9α,15S-dihydroxy-11-oxothromba-5Z,13E-dien-1-oic acid

Synonyms:  11-dehydro TXB2|11-keto TXB2

Molecular weight: 368.5

CAS: 67910-12-7

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Thromboxanes||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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