11β-Prostaglandin F2α MaxSpec® Standard – 100 µg

Brand:
Cayman
CAS:
38432-87-0
Storage:
-20
UN-No:
De Minimis - 1170 / 3

11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 (Item Nos. 12010 | 10007202) in vivo.{493} Normal human urinary excretion of 11β-PGF2α is about 54 ng/mmol creatinine, which is increased nearly 3-fold upon allergen-induced bronchoconstriction in asthmatics.{3519} It is equipotent to PGF2α (Item Nos. 16010 | 10007221) in inducing human bronchial smooth muscle contractions and inhibition of adipose differentiation.{1756,2053} 11β-PGF2α inhibits ADP or thrombin-induced human platelet aggregation at concentrations of 0.14-2.8 µM.{494} 11β-PGF2α MaxSpec® standard is a quantitative grade standard of 11β-PGF2α (Item No. 16520) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 11β-PGF2α MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.  

 

Available on backorder

SKU: 10007224 - 100 µg Category:

Description

A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications,


Formal name: 9α,11β,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid

Synonyms:  11-epi PGF2α|11β-PGF2α

Molecular weight: 354.5

CAS: 38432-87-0

Purity: ≥95%

Formulation: A solution in ethanol at 100 µg/ml


Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards|MaxSpec®||Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway