An oxidized phospholipid; formed in A23187-activated monocytes by direct oxidation of endogenous PE

1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE – 1 mg

Brand:
Cayman
CAS:
947381-58-0
Storage:
-80
UN-No:
Excepted Quantity - 1170 / 3

1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HETE (Item No. 34720) at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (Item No. 11016) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. 25871) by 15-LO.{42427,43514} Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.  

 

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Description

An oxidized phospholipid; formed in A23187-activated monocytes by direct oxidation of endogenous PE

Formal name: 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid, (1R)-2-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-1-[[(1-oxooctadecyl)oxy]methyl]ethyl ester

Synonyms:  15(S)-HETE-SAPE|15(S)-hydroxyeicostetraenoic acid-SAPE|1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine

Molecular weight: 784.1

CAS: 947381-58-0

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Glycerophospholipids||Research Area|Cell Biology|Cell Death|Ferroptosis||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Glycerophospholipids||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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