An LPA analog containing palmitic acid at the sn-1 position

1-Palmitoyl Lysophosphatidic Acid – 10 mg

Brand:
Cayman
CAS:
22002-85-3
Storage:
-20
UN-No:
Non-Hazardous - /

1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} Additionally, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.{15000}  

 

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Description

An LPA analog containing palmitic acid at the sn-1 position

Formal name: 2-hydroxy-3-(phosphonooxy)propyl ester, hexadecanoic acid

Synonyms:  1-Palmitoyl LPA (free acid)

Molecular weight: 410.5

CAS: 22002-85-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Glycerophospholipids||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia||Research Area|Lipid Biochemistry|Glycerophospholipids

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