1-Myristoyl-3-docosanoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and docosanoic acid (Item No. 9000338) at the sn-3 position.
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A diacylglycerol
Formal name: docosanoic acid, 2-hydroxy-3-[(1-oxotetradecyl)oxy]propyl ester
Synonyms: 1-Myristin-3-Behenin|1-Myristoyl-3-Behenoyl-rac-glycerol|DG(14:0/0:0/22:0)
Molecular weight: 625
CAS: 115877-95-7
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Lipids|Glycerolipids||Research Area|Lipid Biochemistry|Glycerolipids
The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 µM compared to 20 µM by resveratrol.{14545}
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The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 µM compared to 20 µM by resveratrol.{14545}
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