A fatty acid glycerol that has been isolated from S. chinensis roots

1-Linoleoyl Glycerol – 10 mg

Brand:
Cayman
CAS:
2277-28-3
Storage:
-80
UN-No:
De Minimis - 1648 / 3

Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of stimulated cells that acts as a mediator of platelet aggregation, inflammation, and allergy.{939,11753} PAF is converted to the biologically inactive lyso-PAF by the enzyme PAF acetylhydrolase (PAF-AH). Recently, plasma PAF-AH has been linked to atherosclerosis and may be a positive risk factor for coronary heart disease in humans.{11455} 1-Linoleoyl glycerol (1-LG) is a fatty acid glycerol that has been isolated from S. chinensis roots. It inhibits PAF-AH with an IC50 of 45 µM.{14173} 1-LG has potential application in cholesterol lowering and antiatherogenic activity.  

 

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Description

A fatty acid glycerol that has been isolated from S. chinensis roots, inhibits PAF-AH with an IC50 value of 45 µM

Formal name: 9Z,12Z-octadecadienoic acid, 1-glyceryl ester

Synonyms:  1-LG

Molecular weight: 354.5

CAS: 2277-28-3

Purity: ≥90%

Formulation: A solution in acetonitrile

Product Type|Biochemicals|Lipids|Glycerolipids||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Lipid Biochemistry|Glycerolipids

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