A synthetic prodrug of 1

1-hydroxy Vitamin D2 – 5 mg

Brand:
Cayman
CAS:
54573-75-0
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity.{15096,19429} 1-hydroxy Vitamin D2 is a synthetic prodrug of the active 1,25-dihydroxy vitamin D2 (Item No. 11174), as well as of other active metabolites.{21568} It is used to suppress the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism, an action which requires vitamin D receptor.{21564,21563,21567} 1-hydroxy Vitamin D2 is effective in stimulating bone growth and, in combination therapy with angiotensin receptor blockers, ameliorates albuminuria and glomerulosclerosis associated with diabetic nephropathy.{21566,21570} It also inhibits the growth of certain blastomas and prostate cancer cells.{21582,21583}  

 

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SKU: 12077 - 5 mg Category:

Description

A synthetic prodrug of 1,25-dihydroxy vitamin D2; used to suppress the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism; stimulates bone growth; inhibits the growth of certain blastomas and prostate cancer cells

Formal name: 4-methylene-5Z-[2E-[(1R,3aS)-octahydro-7aR-methyl-1R-[1R,4,5-trimethyl-2E-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-1,3S-cyclohexanediol

Synonyms:  1-Hydroxyergocalciferol|Doxercalciferol|Hectorol|TSA 840

Molecular weight: 412.7

CAS: 54573-75-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Vitamins||Research Area|Cancer||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Endocrinology & Metabolism|Cofactors & Vitamins||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Vitamin D Receptor||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes

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