A metabolite of bufuralol; used to determine CYP2D enzyme activity in humans and rats

1′-hydroxy Bufuralol – 500 µg

Brand:
Cayman
CAS:
57704-16-2
Storage:
-20
UN-No:
Non-Hazardous - /

1’-hydroxy Bufuralol is a metabolite of bufuralol (Item No. 17794). Bufuralol is metabolized by the cytochrome P450 isoforms 2D1 and 2D2 (CYP2D1/2); therefore, quantification of the bufuralol metabolite, 1’-hydroxy bufuralol, can be used to determine CYP2D1/2 enzyme activity in humans and rats.{37035,37036}  

 

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Description

A metabolite of bufuralol; used to determine CYP2D enzyme activity in humans and rats

Formal name: α2-[[(1,1-dimethylethyl)amino]methyl]-α7-methyl-2,7-benzofurandimethanol

Synonyms:  Ro 03-7410

Molecular weight: 277.4

CAS: 57704-16-2

Purity: ≥97%

Formulation: A solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Toxicology|Drug Metabolism|Cytochrome P450||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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